Title
Adipose tissue as an alternative source for regenerative medicine
Date Issued
01 October 2013
Access level
metadata only access
Resource Type
Controlled Vocabulary for Resource Type Genres::texto::revista::artículo::artículo de revisión
Author(s)
Socarrás-Ferrer B.
del Valle-Pérez L.
de la Cuétara-Bernal K.
Galván-Cabrera J.
Bencomo-Hernández A.
Macías-Abraham C.
Instituto de Hematologia e Inmunologia
Instituto de Hematologia e Inmunologia
El Centro Internacional de Restauración Neurológica
Instituto de Hematologia e Inmunologia
Instituto de Hematologia e Inmunologia
Instituto de Hematologia e Inmunologia
Abstract
Adipose tissue is an alternative source in cell therapy due to various factors such as its easy extraction, its high content of mesenchymal stem cells and their capacity of ex vivo expansion which can be equivalent or even superior to cells obtained from bone marrow in terms of its ability of differentiation potential of angiogenesis and its immunomodulatory effects in inflammation. These cells have the following expression profile: positive staining for CD29, CD44, CD54, CD90, CD105 and HLA-I; and negative for CD45, CD116, CD14, CD31 and HLA-II. At present, there is evidence that the stem cells derived from adipose tissue has have the potential to differentiate in addition to cells of mesodermal origin as neurons, pancreatic cells, endocrine, hepatocytes, cardiomyocytes and epithelial cells, among others. Because of All these factors and the absence of ethical and immunological problems suggest a new possibility in the treatment of many diseases common to everyday medical practice.
Start page
340
End page
348
Volume
29
Issue
4
Subjects
Scopus EID
2-s2.0-84889648147
Source
Revista Cubana De Hematologia Inmunologia Y Hemoterapia
ISSN of the container
15612996
Sources of information: Scopus Directorio de Producción Científica