With the aim of establishing the probable natural formation of graphite oxide (GO) during the weathering and transport of this mineral, a highly crystalline graphite sample isolated from a Sierra Nevada Formation graphitic schist (Precambrian Age) collected at the State of Trujillo, was subject to controlled oxidation in an oven (T̃90°C) with a wet oxygen atmosphere through 25, 50 and 75 days of oxidation. This experimental design simuling weathering is equivalent to the natural alteration for the period of 8, 16 and 24 years, approximately. In addition, graphite oxide (GO) was synthesized by treatment with acid KMnO4. All samples and GO were characterized by means of XRD, Raman spectroscopy, thermogravimetric analysis and Fourier Transformed infrared spectroscopy. Oxydized samples exhibit a decrease in the crystallinity index and in the crystal thickness, reduction of the Raman signals corresponding to the ordered structure, displacements in the highest temperature towards lower values in thermogravimetry, and appearance of C - O strenght vibration in infrared spectroscopy. Such results indicate that a modification takes place in the graphite crystallinity, due to the expansion and incorporation of oxygen. The extent of the alteration do not reached the stage of GO formation.