This research aims to evaluate the effect of three protein levels (15.0, 16.5, and 18.0 %) and three sulfur amino acid levels (0.71, 0.78, and 0.86 %) on hens' production efficiency and egg quality. It used Hy-Line Brown layers (n = 216) at 25 weeks of age. The nine treatments were distributed in a completely randomized design with a 3 x 3 factorial pattern. The experiment lasted 12 weeks. The best egg production was reported by hens fed 18.0 % protein, while the best egg weight value was obtained with 15.0 % protein. The highest weight gain was achieved with diets containing 16.5 % protein. Except for weight gain, there were no significant effects (p > 0.05) of methionine + cystine levels on the factors studied, obtaining the most significant weight gain with a methionine + cystine level of 0.86 %. The highest returns were attained with protein and sulfur amino acid levels of 16.5 and 0.71 % or 15.00 and 0.86 %, respectively.