Title
A simple and improved method for diagnosis of tuberculosis using hypertonic saline and sodium hydroxide to concentrate and decontaminate sputum
Date Issued
01 January 2008
Access level
metadata only access
Resource Type
journal article
Abstract
We report the use of hypertonic saline and sodium hydroxide (HS-SH) for concentration-decontamination of sputum samples for the diagnosis of tuberculosis. This method increases detection of mycobacteria in smears compared to examination of direct smears, is comparable and reduces contamination in cultures compared to NALC-NaOH. © 2008, SAGE Publications. All rights reserved.
Start page
97
End page
99
Volume
38
Issue
2
Language
English
OCDE Knowledge area
Sistema respiratorio
TecnologÃa médica de laboratorio (análisis de muestras, tecnologÃas para el diagnóstico)
Scopus EID
2-s2.0-47549111946
PubMed ID
Source
Tropical Doctor
ISSN of the container
00494755
DOI of the container
10.1258/td.2007.070024
Source funding
Directorate-General for International Cooperation and Development
DGDC
Sponsor(s)
This study was partially supported by the Directorate-General for Development Cooperation of the Belgian Government (DGDC), project 95501. We thank Juan Agapito, from the TB control programme laboratory at Hospital Nacional Cayetano Heredia, for providing the sputum samples; Jose Chauca and Prof Jaime Garcia for their suggestions for statistical analysis; and Dr Mark Swancutt for reviewing this report.
Sources of information:
Directorio de Producción CientÃfica
Scopus