Title
Newly developed primers for comprehensive amplification of the rpoB gene and detection of rifampin resistance in Mycobacterium tuberculosis
Date Issued
01 January 2007
Access level
open access
Resource Type
journal article
Author(s)
Rigouts L.
De Rijk P.
Nduwamahoro E.
Van Deun A.
Ramsay A.
Portaels F.
Abstract
New rpoB gene primers for detecting Rifr in Mycobacterium tuberculosis complex bacteria achieved 100% specificity and 88% (fresh sputa) and 92% (ethanel-preserved sputa) diagnostic sensitivity and detected up to 4 CFU/sample. Of the 99 Rifr isolates examined, 97% had mutations within cluster 1,2% at codon 176, and 1% at codon 497. Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Start page
252
End page
254
Volume
45
Issue
1
Language
English
OCDE Knowledge area
Enfermedades infecciosas
Biología celular, Microbiología
Sistema respiratorio
Scopus EID
2-s2.0-33846248286
PubMed ID
Source
Journal of Clinical Microbiology
ISSN of the container
00951137
Sources of information:
Directorio de Producción Científica
Scopus