Title
Radio frequency-driven recoupling at high magic-angle spinning frequencies: Homonuclear recoupling sans heteronuclear decoupling
Date Issued
05 May 2008
Access level
metadata only access
Resource Type
research article
Author(s)
Ramachandran R.
Caporini M.
Eddy M.
Griffin R.
Massachusetts Institute of Technology
Abstract
We describe solid-state NMR homonuclear recoupling experiments at high magic-angle spinning (MAS) frequencies using the radio frequency-driven recoupling (RFDR) scheme. The effect of heteronuclear decoupling interference during RFDR recoupling at high spinning frequencies is investigated experimentally and via numerical simulations, resulting in the identification of optimal decoupling conditions. The effects of MAS frequency, RF field amplitude, bandwidth, and chemical shift offsets are examined. Most significantly, it is shown that broadband homonuclear correlation spectra can be efficiently obtained using RFDR without decoupling during the mixing period in fully protonated samples, thus considerably reducing the rf power requirements for acquisition of C13 - C13 correlation spectra. The utility of RFDR sans decoupling is demonstrated with broadband correlation spectra of a peptide and a model protein at high MAS frequencies and high magnetic field. © 2008 American Institute of Physics.
Volume
128
Issue
5
Language
English
OCDE Knowledge area
Astronomía Sistemas de automatización, Sistemas de control
Scopus EID
2-s2.0-41449085042
PubMed ID
Source
Journal of Chemical Physics
ISSN of the container
00219606
Sources of information: Directorio de Producción Científica Scopus