Title
Lactulose: Mannitol diagnostic test by HPLC and LC-MSMS platforms: Considerations for field studies of intestinal barrier function and environmental enteropathy
Date Issued
08 October 2014
Access level
open access
Resource Type
journal article
Author(s)
Lee G.O.
Kosek P.
Lima A.A.M.
Singh R.
Yori P.P.
Lamsam J.L.
Oliveira D.B.
Guerrant R.L.
Publisher(s)
Lippincott Williams and Wilkins
Abstract
Objectives: The lactulose: mannitol (L: M) diagnostic test is frequently used in field studies of environmental enteropathy (EE); however, heterogeneity in test administration and disaccharide measurement has limited the comparison of results between studies and populations. We aim to assess the agreement between L: M measurement between high-performance liquid chromatography with pulsed amperometric detection (HPLC-PAD) and liquid chromatography-tandem mass spectrometry (LC-MSMS) platforms.
Start page
544
End page
550
Volume
59
Issue
4
Language
English
OCDE Knowledge area
Gastroenterología, Hepatología
Subjects
Scopus EID
2-s2.0-84917691570
PubMed ID
Source
Journal of Pediatric Gastroenterology and Nutrition
ISSN of the container
02772116
Sources of information:
Directorio de Producción Científica
Scopus