Title
Biclustering of gene expression data based on local nearness
Date Issued
01 December 2006
Access level
metadata only access
Resource Type
conference paper
Author(s)
University of Seville
Abstract
The analysis of gene expression data in DNA chips is an important tool used in genomic research whose main objectives range from the study of the functionality of specific genes and their participation in biological process to the reconstruction of diseases's conditions and their subsequent prognosis. Gene expression data are arranged in matrices where each gene corresponds to one row and every column represents one specific experimental condition. The biclustering techniques have the purpose of finding subsets of genes that show similar activity patterns under a subset of conditions. Our approach consists of a biclustering algorithm based on local nearness. The algorithm searches for biclusters in a greedy fashion, starting with two-genes biclusters and including as much as possible depending on a distance threshold which guarantees the similarity of gene behaviors.
Start page
681
End page
692
Language
English
OCDE Knowledge area
Informática y Ciencias de la Información
Scopus EID
2-s2.0-84873935969
ISBN
2854287185
9782854287189
ISBN of the container
2854287185, 978-285428718-9
Conference
Extraction et Gestion des Connaissances, EGC 2006
Sources of information:
Directorio de Producción Científica
Scopus