The aim of this research was to determine what is known about the domotic system and the quality of life in low-income households, through a systematic review between 2010 and 2021. The study made it possible to review important databases such as Scielo, Scopus, EBSCO, and ScienceDirect. The search combination used “domotic system”; “quality of life”; “domotics”; “technology”; “automation”. Finally, 30 empirical articles in English and Spanish were systematized. In the analyzed literature, it is evident that the lack of knowledge in the concept of home automation, added to the low investment of assets for research and generation of proprietary technology, has caused a slow inclusion of home automation in different places, which is alarming since it includes important issues such as comfort, security, and energy savings that are applied to homes, buildings, and shopping centers. It was possible to reach the conclusion that the use of home automation in homes would include a better living condition in low-income households, oriented to the reduction of duplicated expenses or the efficient use of resources.