Title
Recurrence after treatment for pulmonary multidrug-resistant tuberculosis
Date Issued
15 September 2010
Access level
open access
Resource Type
journal article
Author(s)
Harvard Medical School
Abstract
We estimated the proportion of recurrence within 2 years among adults cured by individualized multidrug-resistant tuberculosis regimens in Peru. Among 310 individuals with at least 24 months of follow-up, 16 experienced an episode of recurrent tuberculosis. If we assume the worst for treatment effectiveness-that all 16 episodes were caused by the original tuberculosis strain-then 5.2% (95% confidence interval, 3.0%-8.2%) experienced true relapse. This is an upper- bound estimate of relapse on which new regimens must improve. © 2010 by the Infectious Diseases Society of America.
Start page
709
End page
711
Volume
51
Issue
6
Language
English
OCDE Knowledge area
Enfermedades infecciosas
Epidemiología
DOI
Scopus EID
2-s2.0-77955956444
PubMed ID
Source
Clinical Infectious Diseases
ISSN of the container
10584838
Sponsor(s)
Financial support. The Charles H. Hood Foundation, the David Rockefeller Center for Latin American Studies at Harvard University, the NEW AID Foundation, the von Clemm Foundation, the Bill & Melinda Gates Foundation, and career development awards from the National Heart, Lung, and Blood Institute (K01 HL080939 to M.C.B.) and the National Institute of Allergy and Infectious Diseases (K01 A1065836 to C.D.M.). Potential conflicts of interest. All authors: no conflicts.
Sources of information:
Directorio de Producción Científica
Scopus