The association of epidermolysis bullosa (EB), congenital localized absence of skin and nail alterations like anonychia and dystrophy has been denominated Bart's syndrome, which was described nineteen years ago, and associated with simple, junctional and dystrophies epidermolysis bullosa. We explain in this study three cases, which because of their clinic characteristics will correspond to this new entity. All of these cases happened in the city of Trujillo, Peru.