Title
Time-Lapse Embryo culture: A better understanding of embryo development and clinical application
Date Issued
01 January 2022
Access level
open access
Resource Type
journal article
Author(s)
Publisher(s)
Sociedade Brasileira de Reproducao Assistida
Abstract
Conventional embryo assessment is performed by removing embryos from incubators at least once a day. However, it is static and limited to specific time points, reducing the amount of information that could potentially be obtained. Fortunately, the time-lapse system is a powerful technology that enables to observe embryo development progression by image acquisition at recurrent time intervals, without interfering in the culture conditions. There are numerous studies that used time-lapse incubators, focusing on embryo kinetics, patient characteristics and clinical outcomes. This review aims to find agreements in the literature concerning embryo kinetics and patient characteristics: age, body mass index, smoking habit, polycystic ovary syndrome and endometriosis; as well as culture conditions that involved culture media and oxygen concentration. Furthermore, they showed differences according to ploidy status, direct/ reverse cleavage, gender and the potential association between embryo collapse and clinical outcomes.
Start page
432
End page
443
Volume
26
Issue
3
Language
English
OCDE Knowledge area
Biología reproductiva
Subjects
Scopus EID
2-s2.0-85134808643
PubMed ID
Source
Jornal Brasileiro de Reproducao Assistida
ISSN of the container
1517-5693
Sources of information:
Directorio de Producción Científica
Scopus