Title
Timed up and go test predicts mortality in older adults in Peru: a population-based cohort study
Date Issued
01 December 2022
Access level
open access
Resource Type
journal article
Author(s)
Publisher(s)
BioMed Central Ltd
Abstract
Background: While there is evidence about stablished risk factors (e.g., raised blood pressure) and higher mortality risk in older population, less has been explored about other functional parameters like the Timed Up and Go test and the Gait Speed in older people at low- and middle-income countries. We aimed to study these mobility tests as predictors of mortality in a population of older people in Peru. Methods: Population-based prospective cohort study (2013–2020). Random sampling of people aged 60+ years in a community of Lima, Peru. Geriatricians conducted all clinical evaluations and laboratory tests were conducted in the local hospital. Participants were sought in the national vital registration system, and we collated cause (ICD-10) and date of death. We conducted a nested forward multivariate Cox proportional hazard model to identify all potential predictors of all-cause, communicable and non-communicable diseases mortality. Results: At baseline, there were 501 older people (mean age 70.6 and 62.8% were women), complete follow-up information was available from 427 people. Mean follow-up time was 46.5 months (SD = 25.3). In multivariate models, the Timed Up and Go test was associated with higher risk of all-cause mortality (HR = 1.05; 95% CI: 1.02–1.09). For cause-specific mortality, history of heart disease (HR = 2.25; 95% CI: 1.07–4.76) and age in years (HR = 1.05; 95% CI: 1.01–1.09) were predictors of non-communicable diseases mortality. Conclusions: In addition to established risk factors for mortality in older population, the Timed Up and Go test, a functional parameter, raised as a relevant predictor of all-cause mortality.
Volume
22
Issue
1
Language
English
OCDE Knowledge area
Ciencias médicas, Ciencias de la salud
Subjects
Scopus EID
2-s2.0-85123012103
PubMed ID
Source
BMC Geriatrics
ISSN of the container
14712318
Sponsor(s)
The authors are grateful to all the geriatricians of the Gerontology Institute of the Universidad Peruana Cayetano Heredia, who perform the geriatric assessment and collect data for this research.
RMC-L is supported by a Wellcome Trust International Training Fellowship (214185/Z/18/Z).
Sources of information:
Directorio de Producción Científica
Scopus