Title
Molecular epidemiology of cystic echinococcosis: Genotypic characterization in humans and different livestock
Other title
Epidemiología molecular de la equinococosis quística: Caracterización genotípica en humanos y diferentes animales
Date Issued
01 December 2016
Access level
open access
Resource Type
journal article
Author(s)
Manterola C.
Universidad de Tarapacá
Publisher(s)
Universidad de la Frontera
Abstract
Echinococcus Granulosus (EG) is the major cause of cystic echinococcosis in humans and livestock in the world. In Chile is a zoonosis of great importance. The most frequently affected geographic areas are the Regions of Aysén, Los Rios, Los Lagos, Coquimbo and the Araucanía. Hence, it was discovered that in endemic areas of hydatidosis there could be several strains and genotypes of EG. In addition, there is evidence that some strains and genotypes are more infectious for human beings than others. This interesting phenomenon of the biology of EG has been studied using molecular biology techniques based on polymerase chain reaction (PCR) and DNA sequence analysis, which has made it possible to characterize the cestode species complex called EG sensu lato (s l) as being comprised of EG sensu stricto (s.s.) (Genotypes G1-G3), E. equinus (G4), E. ortleppi (G5) and E. canadensis (G6-G10), which present an important phenotypic variation detectable in characteristics of the biological cycle, specificity of the intermediate host, pattern of development, pathogenicity, antigenicity, transmission dynamics and, consequently, in the measures needed to control the disease. The aim of this manuscript is to describe the different genotypes of EG described in humans and different livestock host reported in the literature.
Start page
1472
End page
1481
Volume
34
Issue
4
Language
English
OCDE Knowledge area
Epidemiología Parasitología Genética humana
Scopus EID
2-s2.0-85011333412
Source
International Journal of Morphology
ISSN of the container
07179367
Sources of information: Directorio de Producción Científica Scopus