Title
Do Subjective Alcohol Screening Tools Correlate with Biomarkers Among High-Risk Transgender Women and Men Who Have Sex with Men in Lima, Peru?
Date Issued
01 November 2017
Access level
open access
Resource Type
journal article
Author(s)
Herrera M.C.
Leon S.R.
Brown B.
Klausner J.D.
Deiss R.
Hospital Alberto Leonardo Barton Thompson
Publisher(s)
Springer New York LLC
Abstract
Alcohol abuse can influence sexual risk behavior; however, its measurement is not straightforward. This study compared self-reported alcohol use, via the AUDIT and CAGE, with levels of phosphatidylethanol (Peth), a phospholipid biomarker that forms with chronic, heavy drinking, among high-risk MSM and TW in Lima, Peru. Chi square, Fisher’s exact, Wilcoxon ranksum tests compared the instruments. Receiver operating curves determined sensitivity and specificity of the self-reported measures. Among 69 MSM and 17 TW, PEth was positive for 86% (95% CI 77–93%) of participants, while 67% reported binge-drinking in the last 2 weeks. The AUDIT classified 25% as hazardous drinkers while CAGE identified 6% as problem drinkers. Self-reported binge drinking was more sensitive than the AUDIT for PEth positivity (71% vs. 27%, p = 0.022). Among high-risk MSM and TW in Lima, validated, self-report measures of alcohol abuse underestimated biological measures. Further research correlating bio-markers and self-reported alcohol abuse measures is needed.
Start page
253
End page
261
Volume
21
Language
English
OCDE Knowledge area
Enfermedades infecciosas
Abuso de sustancias
Subjects
Scopus EID
2-s2.0-85031495070
PubMed ID
Source
AIDS and Behavior
ISSN of the container
10907165
Sponsor(s)
Funding This research was funded by the UCLA Center for AIDS Research #AI028697 and by NIH 1R01AI099727 and NIH/NIMH R25MH087222.
Acknowledgements The authors would like to thank all study participants and staff for their contributions to this study. This study was partially funded by a seed grant from the UCLA AIDS Institute. We would also like to thank Jina Lee and Helen Houldsworth of the UCLA AIDS Institute for her assistance with study funding and obligations. Finally, we would like to thank Meghan Burke and Joseph Jones of the United States Drug Testing Laboratory for their assistance in obtaining and interpreting phosphatidylethanol test assays.
Sources of information:
Directorio de Producción Científica
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