Title
Evidence of clonal expansion in the genome of a multidrug-resistant Mycobacterium tuberculosis clinical isolate from Peru
Date Issued
2014
Access level
metadata only access
Resource Type
journal article
Author(s)
Publisher(s)
American Society for Microbiology
Abstract
We report the genome sequence of Mycobacterium tuberculosis INS-MDR from Peru, a multidrug-resistant tuberculosis (MDRTB) and Latin American-Mediterranean (LAM) lineage strain. Our analysis showed mutations related to drug resistance in the rpoB (D516V), katG (S315T), kasA (G269S), and pncA (Q10R) genes. Our evidence suggests that INS-MDR may be a clonal expansion related to the African strain KZN 1435.
Volume
2
Issue
1
Language
English
OCDE Knowledge area
Farmacología, Farmacia
Sistema respiratorio
Scopus EID
2-s2.0-84998706922
Source
Genome Announcements
ISSN of the container
2169-8287
Sources of information:
Directorio de Producción Científica
Scopus