As the culmination of the Chemical Engineering curriculum, students face the challenging and stimulating elaboration of a whole design project that integrates all the knowledge gained throughout the course. The subject is divided into two parts, gaining a theoretical background in the ninth semester and a proposed teamwork project design with the aid of a process simulator in the tenth semester. This paper presents the challenge of designing a whiskey distillery elected by a group of students applying the project-based learning methodology. As a strategy for a more efficient design, the process is divided into three blocks: prefermentation, fermentation, and distillation. Calculations involve mass and energy balances and the design of the different units, including the optimization of a distillation column assisted by the ASPEN HYSYS® simulator. Students must publicly present their results in front of the class and a jury formed by chemical engineers. A survey was carried out to assess the student's satisfaction and feedback. The results manifested the significance of the subject for the future and the satisfaction of the proposed teaching strategy.