Even though undergraduate engineering education often considers laboratory experiments as its practical component, these activities may not contribute to the development of soft (professional) skills. At “Universidad de Ingenieria y Tecnologia”, Perú, a series of courses called interdisciplinary projects has been created to promote the development of professional skills through project-based learning; herein, we report the experience of an interdisciplinary group of students focused on designing an indoor air filtration system to improve air quality and to reduce the spread of coronavirus diseases. Eight undergraduate engineering students were organized into three groups and worked collaboratively to learn about antiviral nanocomposites, user-centered design, and electromechanical systems design; they showed their progress and received feedback from each other through weekly meetings. In addition, they leaned on applications to organize the group work and share the bibliography consulted; finally, we collected feedback from these students on the proposed learning method. The positive impact of our problem-based learning approach on undergraduate engineering students is discussed.