Title
Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis
Date Issued
01 May 2005
Access level
open access
Resource Type
journal article
Author(s)
Hawkey C.R.
Yap T.
Pereira J.
Davidson R.N.
Pasvol G.
Onn M.K.
Wall R.A.
Wilkinson R.J.
Northwick Park Hospital
Publisher(s)
Oxford University Press
Abstract
In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immunodeficiency virus-uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 21-139 days) and persisting for a median of 67.5 days (interquartile range, 34-111 days). We found no association between the use of steroids and the duration of reaction. © 2005 by the Infectious Diseases Society of America. All rights reserved.
Start page
1368
End page
1371
Volume
40
Issue
9
Language
English
OCDE Knowledge area
Enfermedades infecciosas
Scopus EID
2-s2.0-17644364112
PubMed ID
Source
Clinical Infectious Diseases
ISSN of the container
10584838
Sponsor(s)
We thank Dr. Mark Harries (North West London Hospitals National Health Service Trust, Harrow, United Kingdom), some of whose patients are described in the present study. We also thank Dr. Sandra Eldridge (Queen Mary College, London, United Kingdom) for statistical advice. Financial support. The Wellcome Trust (grants 064261 and 060079) and the North West London Hospitals National Health Service Trust. Potential conflicts of interest. All authors: no conflicts.
Sources of information: Directorio de Producción Científica Scopus