The objective of this paper was to establish the relationship between using active learning and developing mathematical competencies in third grade Awajún students. The research design was mixed, applied and explanatory, pre-test/post-test. The sample was comprised of 22 third grade students from the Awajún culture in the El Cenepa district, province of Condorcanqui, department of Amazonas, Peru, in 2018. Techniques applied were observation and pedagogical tests, while instruments included a pedagogical test and an observation sheet. According to pretest results, no students reached the meet and master levels in the mathematical skills assessed. The post-test results indicated that 72% of the students reached the meet and master levels after the application of didactics based on active learning. It is concluded that the use of active learning influences the development of mathematics competencies in Awajún third grade students from the El Cenepa district, province of Condorcanqui, department of Amazonas, Peru, in 2018.