Title
CD133 in breast cancer cells and in breast cancer stem cells as another target for immunotherapy
Date Issued
2016
Access level
open access
Resource Type
journal article
Author(s)
Publisher(s)
Masson-Doyma Mexico, S.A.
Abstract
Breast cancer consists of a heterogeneous group of tumors with different features, biology and treatments. Cancer stem cells (CSCs) have been associated with an aggressive cellular behavior, resistance to chemotherapy and radiotherapy in many types of neoplasms, and a strong correlation between prominin-1 (CD133) expression in cancer stem cells from different types of cancer exist. A discussion is presented on recent immunotherapeutic strategies that target CD133 in breast CSCs. Furthermore, it is suggested that immunotherapy targeting CD133 breast CSCs and/or in combination with other current treatments result in a better outcome. © 2016 Sociedad Mexicana de Oncología.
Start page
22
End page
30
Volume
15
Issue
1
Number
12
Language
English
Scopus EID
2-s2.0-84963596865
Source
Gaceta Mexicana de Oncologia
ISSN of the container
1665-9201
Sponsor(s)
To CONCYTEC through CIENCIACTIVA for its financial support.
Sources of information:
Directorio de Producción Científica