Title
Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin
Date Issued
01 July 2017
Access level
open access
Resource Type
journal article
Author(s)
Alves G.
Machado-de-Ávila R.
Silva R.
Lobato F.
Universidade Federal de Minas Gerais
Publisher(s)
Elsevier Editora Ltda
Abstract
The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines.
Start page
570
End page
575
Volume
48
Issue
3
Language
English
OCDE Knowledge area
Toxicología
Scopus EID
2-s2.0-85021418705
PubMed ID
Source
Brazilian Journal of Microbiology
ISSN of the container
15178382
Sponsor(s)
Funding text The authors would like to thank the Minas Gerais Research Support Foundation (Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais ? FAPEMIG), the Brazilian Federal Agency for the Support and Evaluation of Graduate Education (Coordena??o de Aperfei?oamento de Pessoal de Ensino Superior ? CAPES) and the National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico ? CNPq).
Sources of information: Directorio de Producción Científica Scopus