The imminent advance of Nanomedicine is clearly reflected in the implementation of techniques based on drug deliv-ery towards concrete places that are contaminated by anomalous tissues and tumors. A promising as well as robust vehicle are the well- known nanoparticle. Therefore one expects a crucial role of engineered nanoparticles to accomplish exact tasks surpassing known achievements from the side of current pharmacology. However, in all those charged superficially nanoparticles one can expect a latent function that might be a disadvantage as to the main role of targeted drug delivery schemes and medical purposes. In this paper, a theory the apparition of nanocurrents produced a continue accumulation of charged nanoparticles, and that would be caused by diffusive effects is constructed and the consequences from it are identified. Thus, from the results of this paper the explicit dependence of diffusion coefficient is derived. This would acquire relevance in the advanced Oncology that requires of precision and efficiency.