Title
Polyclonal pulmonary tuberculosis infections and risk for multidrug resistance, Lima, Peru
Date Issued
01 November 2017
Access level
open access
Resource Type
journal article
Author(s)
Nathavitharana R.R.
Shi C.X.
Chindelevitch L.
Zhang Z.
Galea J.T.
Contreras C.
Becerra M.C.
Murray M.B.
Cohen T.
Publisher(s)
Centers for Disease Control and Prevention (CDC)
Abstract
Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.
Start page
1887
End page
1890
Volume
23
Issue
11
Language
English
OCDE Knowledge area
Sistema respiratorio
Enfermedades infecciosas
Scopus EID
2-s2.0-85032025947
PubMed ID
Source
Emerging Infectious Diseases
ISSN of the container
10806040
Sponsor(s)
R.R.N. was supported by a Scholar Award from the Harvard Center for AIDS Research (National Institutes of Health [NIH] National Institute of Allergy and Infectious Diseases 2P30AI060354-11) and an Imperial College Global Health Institutional Strategic Support Fund fellowship from the Wellcome Trust. C.X.S. was supported by awards T32MH020031 and P30MH062294 from the NIH National Institute of Mental Health. L.C. was supported by a Natural Sciences and Engineering Research Council of Canada Discovery Grant and a Sloan Foundation Fellowship. L.C. and T.C. received support from an award from the NIH National Institute of General Medical Sciences (U54GM088558). L.C., R.C., Z.Z., J.G., C.C., R.Y., L.L., M.C.B., M.B.M., T.C., and collection of all data presented were supported by NIH (U01AI057786, U19A1076217).
Sources of information:
Directorio de Producción Científica
Scopus