Title
Biclustering on expression data: A review
Date Issued
01 October 2015
Access level
open access
Resource Type
review
Author(s)
Pablo de Olavide University
Publisher(s)
Academic Press Inc.
Abstract
Biclustering has become a popular technique for the study of gene expression data, especially for discovering functionally related gene sets under different subsets of experimental conditions. Most of biclustering approaches use a measure or cost function that determines the quality of biclusters. In such cases, the development of both a suitable heuristics and a good measure for guiding the search are essential for discovering interesting biclusters in an expression matrix. Nevertheless, not all existing biclustering approaches base their search on evaluation measures for biclusters. There exists a diverse set of biclustering tools that follow different strategies and algorithmic concepts which guide the search towards meaningful results. In this paper we present a extensive survey of biclustering approaches, classifying them into two categories according to whether or not use evaluation metrics within the search method: biclustering algorithms based on evaluation measures and non metric-based biclustering algorithms. In both cases, they have been classified according to the type of meta-heuristics which they are based on.
Start page
163
End page
180
Volume
57
Language
English
OCDE Knowledge area
Bioinformática
Subjects
Scopus EID
2-s2.0-84949520835
PubMed ID
Source
Journal of Biomedical Informatics
ISSN of the container
15320464
Sponsor(s)
This research has been supported by the Spanish Ministry of Economy and Competitiveness under Grant TIN2011-28956 .
Sources of information:
Directorio de Producción Científica
Scopus