Title
Kato-Katz and Lumbreras rapid sedimentation test to evaluate helminth prevalence in the setting of a school-based deworming program
Date Issued
02 April 2016
Access level
open access
Resource Type
journal article
Author(s)
Publisher(s)
Taylor and Francis Ltd.
Abstract
The sensitivity of the Kato-Katz test is suboptimal for the evaluation of intestinal helminth prevalence. Moreover, during mass deworming, as helminth egg burden decreases, the sensitivity is likely to decrease. The Lumbreras rapid sedimentation (Lumbreras) is a low-cost non-quantitative test, but may provide useful information in low burden areas. We compared the prevalence of intestinal helminth infections assessed by the Kato-Katz and the Lumbreras rapid sedimentation test on 3 stool specimens from each of 1083 children. The sensitivities were compared using the McNemar paired test. Using the combined outcome of the 3 different stool tests as the standard, Kato-Katz had lower sensitivity than Lumbreras rapid sedimentation tests for Ascaris lumbricoides (85.1% vs. 95.1%, p = 0.03), Hymenolepis nana (77.7% vs. 97.9%, p < 0.01), Trichuris trichura (41.7% vs. 100%, p = 0.01), hookworm (0% vs. 100%, p = 0.01), and Strongyloides stercoralis (0% vs. 88%, p < 0.01). Kato-Katz demonstrated significantly lower sensitivity, missing most T. trichiura, hookworm, and S. stercoralis infections. The combination of Kato-Katz and Lumbreras rapid sedimentation tests enables the detection of more intestinal helminths infections in post-deworming low prevalence areas.
Start page
130
End page
134
Volume
110
Issue
3
Language
English
OCDE Knowledge area
Estudios urbanos
Parasitología
Subjects
Scopus EID
2-s2.0-84982262323
PubMed ID
Source
Pathogens and Global Health
ISSN of the container
20477724
Sponsor(s)
National Institutes of Health.
National Institute of Allergy and Infectious Diseases - R01AI104820.
Fogarty International Center - D43TW007393.
Sources of information:
Directorio de Producción Científica
Scopus