The aim of this paper was to study the factorial invariance of Cognitive Emotional Regulation questionnarie (CERQ) among college students from Lima (Peru) and Cordoba (Argentina), to perform a cross-cultural comparison of cognitive emotion regulation strategies. 345 college students from Lima (men = 26.4%; women = 73.6%) and 358 college students from Córdoba (men = 49.7%; women = 49.7%) were examined. Progressive assessment of the factorial invariance (configural, metric, strong and strict) was performed. The results indicate regarding to configural invariance, the structure invariance of nine oblique factors was verified, and although a detailed analysis identifies a non-invariant functioning in some reactive and intercepts. We conclude that the collected evidence is not enough to develop a model to explain the observed differences, whereupon could ask about it in a future study whether the use of these strategies are relate to specific ideologies and values of each culture.