Objectives: The objective of this study was to determine psychosocial factors and habits associated with functional dyspepsia (FD) in medical interns at the Sullana-Piura II-2 support hospital. Methods: This was a prospective longitudinal study of 24 medical interns who answered five surveys: one baseline survey before beginning their medical internships, and another survey at the end of each rotation. The test “A new questionnaire for the diagnosis of dyspepsia” was used for diagnosis of FD, and all the tests used were validated. For bivariate and multivariate analysis, population averaged generalized estimating equations (PA-GEE) were used, using the binomial family and log link function, to obtain raw relative risks (rRR) and adjusted relative risks (aRR) and their 95% confidence intervals. Results: The mean age was 24.1 years (+/- 1.4), 58% (14) were women. The prevalence of dyspepsia among interns was 32%. Having anxiety (p <0.001, aRR: 5.9, 95% CI: 2.88-12.13) or depression (p = 0.015, aRR: 3.4, 95% CI: 1.27-9.29) were risk factors for FD, obtaining a better score at the end of a rotation was a protective factor (p = 0.020, aRR: 0.8, 95% CI: 0.71-0.97). RRs were adjusted for irritability and consumption of energy drinks. Conclusions: According to the data evaluated, those who have a psycho-social disorder during hospitalization are predisposed to suffer greater risks for gastro-intestinal diseases, so that institutions must have programs to detect and monitor these pathologies.