Title
Mild and rapid method for the generation of o-quinone methide intermediates. Synthesis of puupehedione analogues
Date Issued
19 June 2006
Access level
metadata only access
Resource Type
journal article
Author(s)
Barrero A.
Quílez del Moral J.
Mar Herrador M.
Arteaga P.
Cortés M.
Rosellón A.
University of Granada
Abstract
A route to simpler analogues to bioactive puupehedione derivatives involving a hetero Diels-Alder cycloaddition of a o-quinone methide is described. These intermediate species are generated via fluoride-induced desilylation of silyl derivatives of o-hydroxybenzyl iodides. Remarkable short reaction times and very mild experimental conditions are the main features of this method. © 2006 Elsevier Ltd. All rights reserved.
Start page
6012
End page
6017
Volume
62
Issue
25
Language
English
OCDE Knowledge area
Química
Subjects
Scopus EID
2-s2.0-33646589958
PubMed ID
Source
Tetrahedron
ISSN of the container
00404020
Sponsor(s)
This research was supported by the Spanish Ministry of Science and Technology. Project BQU 2002-03211. The authors thank the Spanish Ministry of Education, Culture and Sport and the Regional Andalucian Government for grant to Antonio Rosellón.
Sources of information:
Directorio de Producción Científica
Scopus