This work was carried out in Jaboticabal (575 m altitude, 21°15′ 22{double acute accent} S and 48° 15′ 58″ W), São Paulo, Brazil, aiming to investigate the effects of cattle manure and nitrogen (urea) doses on radish height and yield. Randomized blocks were used with a 2x4x4 factorial scheme and 3 replications. The treatments were combinations of cultivars (25 and 19), cattle manure doses (0, 25, 50, and 75 t ha-1 dry basis) and N doses (0, 60, 120 and 180 kg ha-1). Increased cattle manure and urea doses provided higher plant height and commercial yield in both cultivars, but the N produced more significant effects than the cattle manure. The maximum commercial yield of cultivar (cv) 19 (20.34 t ha-1) was obtained using 75 t ha-1 of cattle manure and 139 kg ha-1 of N, whereas that of cv 25 (11.90 t ha-1) occurred with 75 t ha-1 of cattle manure and 180 kg ha-1 of N. The maximum economic efficiency doses for cv. 25 were 65.1 t ha-1 and 180 kg ha-1 of cattle manure and N, respectively, whereas those for cv 19 were 63.6 t ha-1 and 144.7 kg ha-1 of cattle manure and N, respectively.