Title
The effects of environmental factors on the virulence of Trichomonas vaginalis
Date Issued
01 December 2012
Access level
metadata only access
Resource Type
journal article
Author(s)
Figueroa-Angulo E.
Rendón-Gandarilla F.
Puente-Rivera J.
Cárdenas-Guerra R.
Ortega-López J.
Quintas-Granados L.
Alvarez-Sánchez M.
Arroyo R.
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional
Publisher(s)
Elsevier
Abstract
This review focused on potential regulatory mechanisms of Trichomonas vaginalis virulence properties, cytoadherence, cytotoxicity, phagocytosis, hemolysis, induction of apoptosis, and immune evasion in response to environmental factors of the human urogenital tract, iron, zinc, and polyamines. Understanding the multifactorial nature of trichomonal pathogenesis and its regulation may help to unravel the survival strategies of trichomonads and to implement prevention policies, opportune diagnosis, and alternative treatments for control of trichomoniasis. © 2012 Institut Pasteur.
Start page
1411
End page
1427
Volume
14
Issue
15
Language
English
OCDE Knowledge area
Biología celular, Microbiología
Enfermedades infecciosas
Subjects
Scopus EID
2-s2.0-84870809803
PubMed ID
Source
Microbes and Infection
ISSN of the container
12864579, 1769714X
Sponsor(s)
The author's research related with the topic of this review was supported, in part, by the CINVESTAV-IPN and by grants from CONACYT ( 58611 , 68949 , 153093 , and 162123 to R.A.; 83808 to M.E.A.S.) and from ICyTDF México ( ICyT-299 and ICyT-219 to R.A.; PIFUTP08-150 to M.E.A.S.). E.E.F.A., F.J.R.G., J.P.R. and R.E.C.G. were scholarship recipients from CONACYT-México. E.E.C.G., F.J.R.G. and J.S.C.C. were also scholarship recipients from ICYTDF. We are grateful to Alfredo Padilla Barberi for his help with the art design, Q.F.B Leticia Ávila-González for her technical assistance, and Martha Aguilar for her secretarial support. We apologize to colleagues whose research was not discussed based on space constraints. We thank all the reviewers for their time and help to improve our manuscript.
Sources of information:
Directorio de Producción Científica
Scopus