Title
Prospects for anticipating kidney damage in type-2 diabetes patients through the sensing of albumin passing through the renal glomerulus
Date Issued
11 April 2017
Access level
metadata only access
Resource Type
conference paper
Publisher(s)
Institute of Electrical and Electronics Engineers Inc.
Abstract
In this paper, we explore the prospects of applicability for the sensing of proteins inside the framework of the IoB NT [1] for anticipating the diabetes kidney disease (DKD), from the identification of negatively charged proteins of albumin which are already passing the glomerular layers located in the kidney. The expected high efficiency of the interfaces between the biochemical domains and the standard electromagnetic networks devices might guarantee a continuous surveillance that aims to identify in time, the beginning of abnormal functionality of kidneys through a dedicate sensing of albumin. Concretely, we focus in the detectability of albumin considering its main noise given by the Tamm-Horsfall's proteins. Our simulations have encountered that the efficiency for sensing of albumin passing the glomerulus might be at least of order of 60% ± 5%.
Start page
257
End page
260
Language
English
OCDE Knowledge area
Endocrinología, Metabolismo (incluyendo diabetes, hormonas)
Urología, Nefrología
Scopus EID
2-s2.0-85018379563
ISBN of the container
9781509041794
Conference
2017 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2017
Sources of information:
Directorio de Producción Científica
Scopus