Title
A Possible Mechanism for Flecainide Induced Dizziness
Date Issued
01 June 2022
Access level
metadata only access
Resource Type
research article
Author(s)
Garaycochea O.
Riesgo Á.
Manrique-Huarte R.
Pérez-Fernández N.
Publisher(s)
Lippincott Williams and Wilkins
Abstract
OBJECTIVE: Flecainide is an oral class IC antiarrhythmic drug whose most common extracardiac adverse reactions are "dizziness" and "visual disturbances." We describe a case of flecainide associated- bilateral vestibulopathy and a literature review of this drug's effect on the vestibular system. PATIENT: Sixty-nine-year-old man with a 3-month history of unsteadiness and dizziness after an increase in the dose of flecainide. INTERVENTIONS: Otologic examination, video head-impulse test, vestibular evoked myogenic potentials, pure tone audiometry and high-resolution magnetic resonance imaging. RESULTS: Otologic examination, including the head-impulse test, and vestibular testing revealed bilateral vestibulopathy. CONCLUSIONS: Dizziness is a common extracardiac adverse reaction of Flecainide. Based on the clinical case that we present and the literature review carried out, we hypothesized that a possible mechanism by which flecainide might cause dizziness and visual disturbances is bilateral vestibulopathy.
Start page
e597
End page
e601
Volume
43
Issue
5
Language
English
OCDE Knowledge area
Otras humanidades Otras ciencias naturales
Scopus EID
2-s2.0-85131106957
PubMed ID
Source
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
ISSN of the container
15317129
Sources of information: Directorio de Producción Científica Scopus