Agricultural productivity in the Peruvian region of Amazonas is being jeopardized by conflicts and inadequate land use, that are ultimately contributing to environmental degradation. Therefore, our aim is to assess land suitability for potato (Solanum tuberosum L.) farming in the Jucusbamba and Tincas microwatersheds located in Amazonas, in order to improve land-use planning and enhance the crop productivity of small-scale farmers. The site selection methodology involved a pair-wise comparison matrix (PCM) and a weighted multicriteria analysis using the Analytical Hierarchy Process (AHP) on selected biophysical and socioeconomical drivers. Simultaneously, land cover mapping was conducted using field samples, remote sensing (RS), geostatistics and geographic information systems (GIS). The results indicated that for potato crop farming, the most important criteria are climatological (30.14%), edaphological (29.16%), topographical (25.72%) and socioeconomical (14.98%) in nature. The final output map indicated that 8.2% (22.91 km2) was highly suitable, 68.5% (190.37 km2) was moderately suitable, 21.6% (60.11 km2) was marginally suitable and 0.0% was not suitable for potato farming. Built-up areas (archaeological sites, urban and road networks) and bodies of water were discarded from this study (4.64 km2). This study intends to promote and guide sustainable agriculture through agricultural land planning.