The Urticaceae are represented in Peru by ten genera and 87 species (Brako & Zarucchi, 1993; Ulloa Ulloa et al., 2004), between herbs, shrubs and trees. Here we recognize 24 species and two infra-specific taxa as endemics, representing six genera. Pilea is the genus with more endemic species. Endemic taxa are found mainly in Very Humid Montane Forests and Mesoandean regions, between 1600 and 3550 m elevation. We applied IUCN categories and criteria to six species. Two endemic Urticaceae have been recorded within Peru's protected areas system.