A special microstructured optical fiber, which may be used in a wavelength-division-multiplexing (WDM) optical fiber transmission system for residual chromatic dispersion compensation, is designed and analyzed. The proposed structure is obtained by introducing a small Ge-doped core at the center of a conventional photonic crystal fiber. The behavior of the resulting geometry has been optimized by a genetic algorithm in conjunction with an efficient vectorial finite element formulation. Numerical results show that the designed photonic crystal fiber exhibits flattened negative dispersion over E+S+C+L+U wavelength bands with an average dispersion of −212 ps · km−1 · nm−1. © 2010, IEEE. All rights reserved.