Title
Scanning tunneling microscopy of metal-coated biomolecules
Date Issued
01 January 1992
Access level
metadata only access
Resource Type
conference paper
Author(s)
Univ. of Oregon
Publisher(s)
Publ by Int Soc for Optical Engineering
Abstract
We present a procedure for imaging metal-coated biomolecules with the scanning tunneling microscope. This procedure is simple, easy to implement and gives reproducible results. The biomolecules are adsorbed on glow discharged mica, then coated with a thin film of platinum- carbon. We have applied this method for visualizing two different kind of biomolecules: planar membranes and DNA molecules. The contrast and lateral resolution of the images are comparable to electron micrographs of the same molecules. The lateral resolution is limited by the grain size of the coating film while the vertical resolution seems to be unaffected for very small coating thickness (less than 3 nm).
Start page
118
End page
126
Volume
1639
Language
English
OCDE Knowledge area
Biomateriales
Bioquímica, Biología molecular
Scopus EID
2-s2.0-0026477547
Source
Proceedings of SPIE - The International Society for Optical Engineering
Resource of which it is part
Proceedings of SPIE - The International Society for Optical Engineering
ISSN of the container
0277786X
ISBN of the container
0819407852
Conference
Scanning Probe Microscopies
Sources of information:
Directorio de Producción Científica
Scopus