Title
Endoscopic Placental Laser Coagulation in Dichorionic and Monochorionic Triplet Pregnancies
Date Issued
01 October 2016
Access level
metadata only access
Resource Type
research article
Author(s)
King's College Hospital
Abstract
Objective: To report the outcome of monochorionic (MC) and dichorionic (DC) triamniotic (TA) triplet pregnancies treated with endoscopic laser coagulation of the communicating placental vessels for severe feto-fetal transfusion syndrome (FFTS) and selective fetal growth restriction (sFGR). Methods: Laser surgery was performed at 18 (15-24) weeks' gestation in 11 MCTA and 33 DCTA pregnancies complicated by FFTS and 14 DCTA pregnancies complicated by sFGR. Data from our study and previous reports were pooled using meta-analytic techniques. Results: Survival of at least one baby and survival among all fetuses was 97.0 and 72.7% in DCTA pregnancies with FFTS, 78.6 and 52.4% in DCTA pregnancies with sFGR and 81.8 and 39.4% in MCTA pregnancies with FFTS. In the combined data from our study and previous reports, the pooled survival rates in 132 DCTA pregnancies with FFTS were 94.4 and 76.1%, and in 29 MCTA pregnancies with FFTS, they were 80.6 and 57.5%. Conclusions: Survival after laser surgery is higher in DC triplets with FFTS than in those with sFGR and in DC than in MC triplets with FFTS.
Start page
174
End page
180
Volume
40
Issue
3
Language
English
OCDE Knowledge area
GastroenterologĂa, HepatologĂa
Subjects
Scopus EID
2-s2.0-84959206130
PubMed ID
Source
Fetal Diagnosis and Therapy
ISSN of the container
10153837
Sponsor(s)
The study was supported by a grant from the Fetal Medicine Foundation (Charity No. 1037116). This paper is part of the PhD thesis of Gergana Peeva for Universidad Autonoma de Madrid.
Sources of information:
Directorio de ProducciĂ³n CientĂfica
Scopus