Objective of this article is to demonstrate the theoretical inconsistency that exists between science, technology and innovation with the theoretical model on which it is based, because it does not have a fully defined study subject. A qualitative, exploratory research of the specialized bibliography was carried out. It was found that both history and philosophy state that science, technology and innovation represent a greater reality than technology transfer, that existing models generate development only when they are applied in the countries that represent their reality. It is concluded that there is a need to define the study subject of science, technology and innovation so that the technology transfer model is subordinated to it. © 2022 IEEE.