Title
Context-sensitive patch histograms for detecting rare events in histopathological data
Date Issued
01 January 2017
Access level
metadata only access
Resource Type
conference paper
Author(s)
Technical Univeristy of Munich
Publisher(s)
SPIE
Abstract
Assessment of histopathological data is not only difficult due to its varying appearance, e.g. caused by staining artifacts, but also due to its sheer size: Common whole slice images feature a resolution of 6000x4000 pixels. Therefore, finding rare events in such data sets is a challenging and tedious task and developing sophisticated computerized tools is not easy, especially when no or little training data is available. In this work, we propose learning-free yet effective approach based on context sensitive patch-histograms in order to find extramedullary hematopoiesis events in Hematoxylin-Eosin-stained images. When combined with a simple nucleus detector, one can achieve performance levels in terms of sensitivity 0.7146, specificity 0.8476 and accuracy 0.8353 which are very well comparable to a recently published approach based on random forests.
Volume
10140
Number
101400F
Language
English
OCDE Knowledge area
Ciencias de la computación
Ciencias de la información
Subjects
Scopus EID
2-s2.0-85020273664
ISSN of the container
16057422
ISBN of the container
978-151060725-5
Conference
Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Sources of information:
Directorio de Producción Científica
Scopus