Objective: To determine the sexual health practices in adolescents from two schools in the province of Cañete, Lima Region. Method: Cross-sectional descriptive study carried out in adolescents between 15 and 17 years of age. Results: A total of 127 students were included. 50.4% (64) were women. The average age was 15.67 ± 0.65. The 24% (30) of the students had started sexual relations. Males were more likely to initiate sexual intercourse than females (OR = 4.67 95% CI [1.83-11.95]; p = 0.001) and access to health services (OR = 2.51 CI95 % [1,065-5,92]; p = 0.032). Women were more likely to receive sexual education from their parents (OR = 2.2 95% CI [1.05-4.65]; p = 0.035). Conclusions: The beginning of sexual relations in the students was within that reported in the national literature, the men were more likely to initiate sexual relations and the women were more likely to receive sexual education from their parents.