The main objective of the research was to try to see the perception of virtual classes and the possible academic repercussions that university students had in Peru, and their associated factors, during the COVID-19 pandemic. Analytical cross-sectional study in Peruvian university students during the first wave of the pandemic, the variable that mediates perception was obtained through a validated scale. In the analytical statistics, it was found that women had a higher frequency of perception of academic repercussions (PRa: 1.37; 95% CI: 1.18-1.59; p value <0.001), this adjusted for age, study career and university. Women were the ones who perceived the most repercussions. Although an association was only found with the sex of the respondents, larger studies should be carried out and in more advanced stages of the pandemic, since our results can be taken as baseline, but the influence of others should be followed up and determine the influence of other variables.