Title
Additional evidence to support the phasing-out of treatment category II regimen for pulmonary tuberculosis in Peru
Date Issued
01 August 2012
Access level
metadata only access
Resource Type
journal article
Author(s)
Publisher(s)
Oxford University Press
Abstract
The effectiveness of the World Health Organization's (WHO) treatment category II regimen for tuberculosis in 124 patients was compared to that of 1147 patients receiving treatment category I in Lima, Peru following WHO's guidelines. Drug susceptibility test was available for 85% of patients. Prevalence of multi drug resistance and streptomycin resistance were 5.1% and 20.7%, respectively. Overall cure rate for regimen II was lower than that of regimen I: 67.8% (95% CI: 58.9-75.6.) vs 77.8% (95% CI: 75.3-80.2), p = 0.014. Multi-drug resistance exerted a profound effect on cure rates in both regimens. Our results support the phasing-out of treatment category II regimen in Peru. © 2012 Royal Society of Tropical Medicine and Hygiene.
Start page
508
End page
510
Volume
106
Issue
8
Language
English
OCDE Knowledge area
Enfermedades infecciosas
Farmacología, Farmacia
Subjects
Scopus EID
2-s2.0-84863579155
PubMed ID
Source
Transactions of the Royal Society of Tropical Medicine and Hygiene
ISSN of the container
00359203
Sources of information:
Directorio de Producción Científica
Scopus