The Aedes aegypti mosquito is a recognized vector for dengue, chikungunya, and Zika arboviruses, and has had a significant dispersion in recent years across the southern hemisphere. Still, even now, the Aedes aegypti is reported to be expanding into regions with temperate climates such as European countries and parts of North America. The impact on public health has been tremendous in terms of morbidity and mortality. Environments that favor more adult mosquitoes and transmission of disease (rapid urban growth, lack of adequate water supply, and lack of solid waste disposal) are associated with high rates of mosquito bites and risk of infection. In the peridomestic environment, stored water and discarded non-biodegradable containers accumulate rainwater and can become a habitat for the development of the immature Aedes aegypti. It is an efficient vector for arboviruses chiefly due to its biting patterns. The vector control measures against the growing immature Aedes aegypti have not been successful. The indices for immature mosquitoes are not demonstrated to be a reliable predictor for human dengue infection risk. Indoor space spraying, a method to control for the adult Aedes aegypti is effective during outbreaks; however, when using such chemical options, resistance to insecticide is a threat and a growing problem. Recently, the interventions of release insects with dominant lethality (RIDL) and Wolbachia have been developed to fight against dengue fever and Zika virus. These strategies have proven to reduce the incidence in many clinical trials, and more studies are being conducted to determine the long-term impact and sustainability.