Study region: The upper part of the Guayllabamba and Napo basins (78.2 ° W, 0.3 °S; 18,500 km2) in the equatorial Andes, which are vulnerable to stress on the ecosystem services. Study focus: This paper analyses the diurnal cycle of precipitation over a transect from the Andes to the Amazon. The diurnal cycle is estimated as the diurnal distribution of precipitation for 2014–2019 using records from 80 stations. Cluster analysis performed on the diurnal cycle estimates depicts the spatial association between the diurnal and seasonal cycles of precipitation. New hydrological insights: A northwest-southeast spatial variation in the diurnal and seasonal cycles is identified with four groups of stations. In the western part, the seasonal cycles of Groups 1 and 2 are bimodal with precipitation maxima in the March-April and October-November seasons and a short drier season in July-August. In the eastern part, Group 3 also presents bimodality, but a weaker seasonal cycle. Conversely, Group 4 is unimodal with a peak in June. Distinct diurnal cycles are observed in both drier and wetter seasons of Groups 1–3; no marked diurnal cycle is observed in Group 4. Groups 3 and 4 are the most spatially heterogeneous, with an exceptional horizontal variation of 330 mm/yr/km. The analysis of these variations provides insight into the atmospheric dynamics driving precipitation in this zone, and may help to better optimize the water supply system.