In a greenhouse we find multiple variables that have great impacts on crops, for this a CFD model is built to simulate microclimate distribution and obtain optimal climate control for the growth of the crop. Analyzes of solar heat gains, heat losses, and temperature and air distributions for each special moment provide a good guide for product selection. In the CFD simulation the greenhouse volume and wind speed will be obtained for an optimal temperature distribution. The time required for maintenance, the need for sensor calibration, natural deterioration, and unexpected failures will have to be taken into account. The analyzes show a comparison between various variations of the air flow velocity in 0.5 m / s, 1 m / s and 1.5 m / s in two different models of greenhouses, which we will obtain the optimal model for the development and elaboration of a greenhouse. Demonstrating the efficiency of CFD models for the design, simulation and application of greenhouses.