Title
Spatial patterns in discordant diagnostic test results for chagas disease: Links to transmission hotspots
Date Issued
15 April 2009
Access level
open access
Resource Type
journal article
Author(s)
Bowman N.M.
Kawai V.
Plotkin J.B.
Waller L.A.
Steurer F.
Seitz A.E.
Carpio J.G.C.D.
McKenzie F.E.
Maguire J.H.
Bern C.
University of Pennsylvania
Publisher(s)
Oxford University Press
Abstract
Diagnosis of Chagas disease is hindered by discordance between screening and confirmatory test results for Trypanosoma cruzi infection. In periurban Arequipa, Peru, spatial analysis revealed that individuals with discordant test results are spatially clustered in hotspots of T. cruzi transmission, suggesting that discordant results likely represent true infections in this setting. © 2009 by the Infectious Diseases Society of America. All rights reserved.
Start page
1104
End page
1106
Volume
48
Issue
8
Language
English
OCDE Knowledge area
Biología celular, Microbiología
Enfermedades infecciosas
DOI
Scopus EID
2-s2.0-63649103891
PubMed ID
Source
Clinical Infectious Diseases
ISSN of the container
10584838
Sponsor(s)
1Fogarty International Center, National Institutes of Health, Bethesda, and 2Johns Hopkins Hospital and 3Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; 4Biology Department, University of Pennsylvania, Philadelphia; 5Program in Population Biology, Ecology, and Evolution, Division of Biological and Biomedical Sciences, Emory University, and 6Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia; 7Division of Infectious Disease, Brigham and Women’s Hospital, Boston, Massachusetts; 8Asociación Benéfica Proyectos en Informática, Salud, Medicina y Agricultura (AB PRISMA), Lima, and 9Dirección Regional del Ministerio de Salud, Arequipa, Perú
Financial support. National Institutes of Health (5P50AI074285-02, R01-ES015525, U19-AI-33061, RO1-AI047498; NIAID grant K01AI079162 to M.Z.L. and training grant 5T35AI007646-03 to N.M.B.), Fogarty/Ellison fellowship to N.M.B., the International Society for Infectious Diseases grant to V.K. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. Potential conflicts of interest. All authors: no conflicts.
Sources of information:
Directorio de Producción Científica
Scopus