The Portulacaceae are represented in Peru by six genera and 26 species (Brako & Zarucchi, 1993), all herbs and subshrubs. Here we recognize seven endemic species in three genera. These endemic species come from mostly Subtropical Costal Desert, between 100 and 800 m elevation. We apply IUCN categories and criteria to three species. Apparently, none of these endemic species has been found in the Peruvian System of Protected Natural Areas.