cris.boxmetadata.label.title
Cancer Cells Microsurgery via Asymmetric Bent Surface Au/Ag/Ni Microrobotic Scalpels through a Transversal Rotating Magnetic Field
cris.boxmetadata.label.dateissued
28 browse.startsWith.months.july 2020
cris.boxmetadata.label.accesslevel
metadata only access
cris.boxmetadata.label.resourcetype
journal article
cris.boxmetadata.label.authors
University of Chemistry and Technology
cris.boxmetadata.label.publisher
American Chemical Society
cris.boxmetadata.label.abstract
The actuation of micro/nanomachines by means of a magnetic field is a promising fuel-free way to transport cargo in microscale dimensions. This type of movement has been extensively studied for a variety of micro/nanomachine designs, and a special magnetic field configuration results in a near-surface walking. We developed "walking"micromachines which transversally move in a magnetic field, and we used them as microrobotic scalpels to enter and exit an individual cancer cell and cut a small cellular fragment. In these microscalpels, the center of mass lies approximately in the middle of their length. The microrobotic scalpels show good propulsion efficiency and high step-out frequencies of the magnetic field. Au/Ag/Ni microrobotic scalpels controlled by a transversal rotating magnetic field can enter the cytoplasm of cancer cells and also are able to remove a piece of the cytosol while leaving the cytoplasmic membrane intact in a microsurgery-like manner. We believe that this concept can be further developed for potential biological or medical applications.
cris.boxmetadata.label.citationstartpage
8247
cris.boxmetadata.label.citationendpage
8256
cris.boxmetadata.label.volume
14
cris.boxmetadata.label.issue
7
cris.boxmetadata.label.language
English
cris.boxmetadata.label.ocdeknowledgeArea
Oncología
Bioquímica, Biología molecular
cris.boxmetadata.label.subjects
cris.boxmetadata.label.doi
cris.boxmetadata.label.scopusidentifier
2-s2.0-85087004011
cris.boxmetadata.label.pubmedidentifier
cris.boxmetadata.label.source
ACS Nano
cris.boxmetadata.label.containerissn
19360851
cris.boxmetadata.label.sponsor
This work was supported by the project Advanced Functional Nanorobots (reg. no. CZ.02.1.01/0.0/0.0/15_003/0000444 financed by the EFRR).
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Directorio de Producción Científica
Scopus