One-dimensional thermal wave transport in multilayered systems with an interface thermal resistance is studied under the framework of the Cattaneo-Vernotte hyperbolic heat conduction model, considering modulated heat excitation under Dirichlet and Neumann boundary conditions. For a single semi-infinite layer, analytical formulas useful in the measurement of its thermal relaxation time as well as additional thermal properties are presented. For a composite-layered system, in the thermally thin regime, with the Dirichlet boundary condition, the well known effective thermal resistance formula is obtained, while for the Neumann problem, only the heat capacity identity is found. In contrast, in the thermally thick case, an analytical expression for both Dirichlet and Neumann conditions is obtained for the effective thermal diffusivity of the whole system in terms of the thermal properties of the individual layers and their interface thermal resistance. The limits of applicability of this equation, in the thermally thick regime, are shown to provide useful and simple results in the characterization of layered systems and that they can be reduced to the results obtained using the Fourier approach. The role of the thermal relaxation time, the interface thermal resistance, and the implications of these results in the possibility of enhancement in heat transport are discussed. © Springer Science+Business Media, LLC 2010.